A first-half penalty won and converted by Mohamed Ibrahim put Zamalek in front for most of the game.
But Ahmed Salem Safi grabbed a 77th minute equalizer to make it 1-1.
Zamalek star Ibrahim was unlucky to see his attempt to save the goal hampered when he slipped on the goal line.
Fans incident
A few before Hodoud's leveller, some 25 fans - believed to be Zamalek ultras - appeared with flares in the stands.
The referee was forced to halt play for a few seconds but opted to resume the match swiftly before the supporters disappeared.
Playing as the home side at Cairo Stadium, it was rumored that Zamalek could lose the match points of the behind-closed-doors tie.
A similar incident occurred last season when the Whites lost 2-1 at home to Police Union.
Zamalek 1-1 Hodoud
Ibrahim goal
Safi goal
Incident