كتب : Omar AbdelAziz
Barcelona ace Lionel Messi put the visitors in front nine minutes from the break with a trademark individual effort, but Colombia equalized from a perfectly-placed Ruben Bustos free kick.
Seven minutes from time, Dayro Moreno scored the decisive winner for Colombia when he hit an empty net.
Manchester United forward Carlos Tevez was shown straight red after just 25 minutes, for being caught by the linesman kicking Colombia's Bustos.
Argentina are still top of the 10-team South American league with nine points from four games, while Colombia jumped to second on eight points.