The five-time champions were held to a 3-3 draw by Angola a few days before the tournament.
Emad Meteb, who forgot to bring his scoring boots to Ghana, notched a treble for Egypt while Flavio registered twice for Angola and Manucho added the third.
Angola ace Flavio knows all about Egyptian football and so does his Ahli teammate Sebastiao Gilberto.
The Pharaohs sacrificed a cow at the training ground on Friday as they seem to be sharpening knives for the Angolan team, known as 'Palancas Negras' or The Black Antelopes.
Egypt
"We came here to win. Our responsibility is greater than the other teams here in Ghana because we are the defending champions. We're here to retain our title,'' said Hassan Shehata.
Team News: Shehata has a full-bore team as the Egypt tactician is more likely to field the same starting eleven who impressed against Cameroon and Sudan.
Center-half Mahmoud Fathallah returns from suspension, and will be pushing for a start at the expense of Shadi Mohamed.
Probable Line-up: Al-Hadari- Gomaa, Fathallah, Moawad, Fathi, H.Saied- Abd-Rabou, Shawky, Zidan- Zaki, Meteb.
Angola
"For the first time we have taken Angola to the next stage of the tournament. But we intend to extend our run," said coach Luis Oliveira Goncalves.
"We are ready for the fourth game, but we are also thinking about the fifth. We don't want to stop here; we want to get to the semi-finals.''
Team News: The Palancas Negras are boosted by the return of captain Luis Figueiredo, who was injured throughout the previous two games.
Probable Line-up: Lama- Kali, Rui Marques, Yamba Asha, Airosa- Gilberto, Macanga, Figueiredo, Ze Kalanga- Flavio, Manucho.