The 33-year-old notched a brace in Juve's 3-3 Serie A draw with Sampdoria to take his tally to 21 goals and occupy top spot in the scorers' chart.
Only Genoa striker Marco Borriello, who scored 19 goals so far, can overtake him when his side face Atalanta in their final Serie A game on Sunday.
Juventus coach Claudio Ranieri believes Del Piero deserves a place in Italy's squad for Euro 2008, which will be played in Austria and Switzerland.
"He has had an extraordinary championship and the choice is up to Donadoni. I am very happy for him," Ranieri was quoted as saying by Calcio Italia magazine.
Del Piero put Juventus ahead after seven minutes before David Trezeguet doubled the lead nine minutes later from the penalty spot.
Two goals from Antonio Cassano and Christian Maggio brought Sampdoria level but Del Piero struck home again in the 65th minute to restore the Bianconeri's lead.
Former Roma striker Vincenzo Montella secured a share of spoils nine minutes from time.