كتب : Omar AbdelAziz
The Arsenal striker is nursing a hamstring injury, but could still catch up with the Oranje's trip to Norway next week.
Van Persie joins injury-prone Real Madrid winger Arjen Robben and Celtic striker Jan Vennegoor of Hesselink, who were both ruled out with injuries.
Defender John Heitinga is also struggling with a knee injury, as Jan Kromkamp is likely to be his replacement.