كتب : Omar AbdelAziz
The veteran forward was taken off the Serie A clash after just 30 minutes, and scans confirmed a damaged thigh muscle.
"Examinations we did this morning showed there is a thigh muscle injury but it was not possible to tell the entity of the problem," said a Roma spokesman.
Initial thoughts suggest that the 32-year-old will be out for at least a month, which means he will miss the crunch league game with AC Milan on January 11th.
Totti was plagued by several injury problems in recent years, a factor which prompted his decision to quit international football.
The Giallorossi icon returned from a serious knee injury at the start of this season, following an anterior cruciate ligament operation earlier this year.