كتب : Omar AbdelAziz
Goals from Bojan Krkic and Eidur Gudjohnsen sealed the win for the Catalans, despite Florent Sinama-Pongolle's earlier scare for the visitors.
Barcelona, who counted on a 3-1 first-leg victory, rested a number of key players including Xavi Hernandez, Lionel Messi, Thierry Henry and Samuel Eto'o.
The Primera Liga leaders will face bitter city rivals Espanyol in the last eight stage of the competition.