The influential playmaker was doubtful for the crucial encounter after he limped off Roma's training on Friday with an inflammation in his right knee.

However, Sky Italia confirmed that after training on Saturday, the 32-year-old will have a place in the Romans' squad against Jose Mourinho's team.

Totti's return will be a massive boost for Roma coach Luciano Spaletti, who's already without Simone Perrotta, Juan, Simone Loria, Alberto Aquilani, Max Tonetto and Marco Casetti.

Veteran defender Christian Panucci was named for his first game in over a month, after the player was overlooked by Spalletti for refusing to sit on the bench against Napoli in January.

Following the incident, Panucci declared that he wants to leave the club but the 35-year-old couldn’t find any suitors before the closure of January's transfer window.

While Inter are leading Serie A with 59 points, nine ahead of their nearest rivals Juventus, Roma are in sixth position with 43 points.