Shikabala was left out of last week's win over Petrojet as he had a personal problem, according to Zamalek's official site.
But the 23-year-old is now ready to spearhead the White Knights in the rescheduled Egyptian Premier League clash.
Moreover, Zamalek were boosted by the news that captain Al-Sayed will shrug off a minor knock and is ready to retain his place between the posts.
Mohamed Al-Morsi returned to the squad at the expense of Ivorian striker Ollie Koffi.
Zamalek Squad:
Goalkeepers: Abdul-Wahed Al-Sayed, Mohamed Abdul-Monsef.
Defenders: Hani Saied, Mahmoud Fathallah, Amr Adel, Amr Al-Safti, Ahmed Magdi, Sabri Rahil, Ahmed Ghanem, Hazem Emam.
Midfielders: Mohamed Abdullah, Alaa Ali, Ahmed Al-Merghani, Ibrahim Salah, Alaa Kamal, Ahmed Abdul-Raouf, Shikabala.
Strikers: Sherif Ashraf, Abdul-Halim Ali, Mohamed Al-Morsi.