كتب : وكالات
Fernando Amorebieta was given a straight red card on 33 minutes as Seydou Keita and Xavi gave the visitors a double lead after the break.
Barcelona's David Villa ensured an edgy end to the game when he received his marching orders on 86 minutes, three minutes before Igor Gabilondo pulled one back for the hosts.
Bilbao went for the equalizer with all men out in attack, only for Sergio Busquests to put the game to bed with first ever Barca goal in the 90th minute.
Barca lie second on 12 points, one behind leaders Valencia.
It remains to be seen whether Villa will be suspended for one game or a further ban will be imposed against him after the straight red card.