كتب : وكالات
The England striker was taken off United's 2-2 Premiership draw at Bolton on Sunday, even so he didn’t seem to be injured.
United has not yet determined the extent of the injury of the 24-year-old, who has been nowhere near his best form so far this term.
The Red Devils, who lie second of the league, succumbed to a disappointing home draw with Rangers in their Champions League opener a fortnight ago.
Valencia lead Group C after thrashing Turkish champions Bursaspor 4-0 away.