كتب : وكالات
The Egypt forward replaced Kevin Grobkreutz on 69 minutes when his side were maintaining a slender lead.
But Petar SliSkovic brought the score level one minute from time to end the match in a stalemate.
Dortmund's Mats Hummels netted the opener only after eight minutes.
Zidan, who plied his trade at Mainz from 2005 until 2007, couldn't make a notable impact in the game.
After shaking off a rib injury, he made his comeback against Hoffenheim a week ago in a league match that saw Dortmund's unbeaten run end.
Dortmund remain on top of the Bundesliga table with 62 points, ten clear of closest rivals Bayer Leverkusen.